Private detective Adrian Monk has brains, instincts, a photographic memory and more than a few obsessive-compulsive disorders. These traits, his ever-present handy wipes and his devoted assistant, Natalie Teeger, help him as he solves cases involving amnesia, betrayal, first loves, true loves and of course, murder. Along with Capt. Stottlemeyer and Lt. Disher, Monk is on the case and more germaphobic than ever.